We seek to understand how chemical signals control physiology and behavior by investigating the molecular basis of these complex processes. Individual cells in the body sense and respond to chemical cues via cell surface receptors, which bind to the ligand and initiate a complex cascade of intracellular events to help the cell adapt to the stimulus. Our research focuses on the largest and most versatile class of signaling receptors in mammalian cells- the G-protein coupled receptors (GPCRs). We apply a combination of high-throughput quantitative approaches and cell biology techniques to systematically dissect the mechanisms and consequences of GPCR signaling. Click below to learn more about our research interests!